Reticulocyte membrane remodeling: contribution of the exosome pathway.

  title={Reticulocyte membrane remodeling: contribution of the exosome pathway.},
  author={Lionel Blanc and Michel Vidal},
  journal={Current opinion in hematology},
  volume={17 3},
PURPOSE OF REVIEW In addition to the loss of all the internal compartments, reticulocyte maturation is characterized by an extensive membrane remodeling. Exosomal secretion contributes to this process by eliminating specific proteins. RECENT FINDINGS Regulation in the exosomal sorting of the water channel aquaporin-1 represents a newly described mechanism by which reticulocytes could adapt to environmental modifications. The extracellular osmotic conditions found in the peripheral circulation… CONTINUE READING