Rethinking the heterosexual infectivity of HIV-1: a systematic review and meta-analysis.

@article{Powers2008RethinkingTH,
  title={Rethinking the heterosexual infectivity of HIV-1: a systematic review and meta-analysis.},
  author={Kimberly A Powers and C. Poole and Audrey E Pettifor and Myron S. Cohen},
  journal={The Lancet. Infectious diseases},
  year={2008},
  volume={8 9},
  pages={
          553-63
        }
}
Studies of cumulative HIV incidence suggest that cofactors such as genital ulcer disease, HIV disease stage, and male circumcision influence HIV transmission; however, the heterosexual infectivity of HIV-1 is commonly cited as a fixed value (approximately 0.001, or one transmission per 1000 contacts). We sought to estimate transmission cofactor effects on the heterosexual infectivity of HIV-1 and to quantify the extent to which study methods have affected infectivity estimates. We undertook a… CONTINUE READING
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