Rethinking the formula

  title={Rethinking the formula},
  author={Roxanne Khamsi},
  journal={Nature Medicine},
Health insurance covers drugs approved by regulatory agencies, but it often doesn't pay for the products known as 'medical foods' needed to keep individuals alive and well. This lack of reimbursement means that many who cannot afford these life-saving diets suffer brain deterioration and disability—or worse. Roxanne Khamsi reports on the battle for medical foods and how it could affect the treatment of diseases as diverse as osteoporosis and Alzheimer's. 
2 Citations
Phenylketonuria (PKU)
What is Phenylketonuria? Phenylketonuria (also known as PKU) is an inherited condition that affects the way a person’s body uses protein. A person with PKU cannot use a component of protein calledExpand


Nutritional treatment for inborn errors of metabolism: indications, regulations, and availability of medical foods and dietary supplements using phenylketonuria as an example.
The nutritional treatment of phenylketonuria is used as an example of IEM treatment and a discussion of the problems that have contributed to the paradox of identifying individuals with IEM through newborn screening but not guaranteeing that they receive optimal treatment. Expand
Care of the adult with phenylketonuria
Following up at an average age of 22 years revealed that the cohort remaining on dietary treatment have achieved substantially better social and academic achievement than the 24 who discontinued dietary treatment. Expand
Improved nutritional management of phenylketonuria by using a diet containing glycomacropeptide compared with amino acids.
GMP, when supplemented with limiting AAs, is a safe and highly acceptable alternative to synthetic AAs as the primary protein source in the nutritional management of PKU and improves protein retention and phenylalanine utilization compared with AAs. Expand