Rethinking pheochromocytomas and paragangliomas from a genomic perspective

@article{CastroVega2016RethinkingPA,
  title={Rethinking pheochromocytomas and paragangliomas from a genomic perspective},
  author={Luis-Jaime Castro-Vega and Charlotte Lepoutre-Lussey and Anne-Paule Gimenez-Roqueplo and Judith Favier},
  journal={Oncogene},
  year={2016},
  volume={35},
  pages={1080-1089}
}
Pheochromocytomas (PCC) and paragangliomas (PGL) are rare neuroendocrine tumors of neural crest origin. These tumors are caused by germline or somatic mutations in known susceptibility genes in up to 70% of cases. Over the past few years, the emergence of high-throughput technologies has enabled the unprecedented characterization of genomic alterations in… CONTINUE READING