Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea

@inproceedings{Oiticica2010RetentionOP,
  title={Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea},
  author={Jeanne Oiticica and Luiz Carlos M Barboza-Junior and Ana C Batissoco and Karina Lezirovitz and Regina C{\'e}lia Mingroni-Netto and Luciana Amaral Haddad and Ricardo Ferreira Bento},
  booktitle={Journal of Translational Medicine},
  year={2010}
}
Culturing otospheres from dissociated organ of Corti is an appropriate starting point aiming at the development of cell therapy for hair cell loss. Although guinea pigs have been widely used as an excellent experimental model for studying the biology of the inner ear, the mouse cochlea has been more suitable for yielding otospheres in vitro. The aim of this study was to compare conditions and outcomes of otosphere suspension cultures from dissociated organ of Corti of either mouse or guinea pig… CONTINUE READING
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