Retention of functional DC-NK cross-talk following up to 18 weeks therapy interruptions in chronically suppressed HIV type 1+ subjects.

Editor: Chronic viral replication during HIV-I infection results, among other effects, in the depletion of dendritic cell (DC) subsets, 2 and decrease of natural killer cells (NK) frequency and function. An inverse correlation between chronic viral replication and numbers of mature NK or DC cells together with a lack of DC-associated functions has been… CONTINUE READING