Retention and biodistribution of microspheres injected into ischemic myocardium.

Abstract

Intramyocardial injection of therapeutic agents may enhance heart repair after infarction. Incomplete retention of intramyocardial injections has been reported, but modes of loss are undefined. We determined the fate of neutron-activated microspheres injected into acutely ischemic rat myocardium using saline, Pluronic F127, or Matrigel as vehicle. Twenty… (More)
DOI: 10.1002/jbm.a.31917

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@article{Anderl2009RetentionAB, title={Retention and biodistribution of microspheres injected into ischemic myocardium.}, author={Jeff N Anderl and Thomas Robey and Patrick S. Stayton and Charles E. Murry}, journal={Journal of biomedical materials research. Part A}, year={2009}, volume={88 3}, pages={704-10} }