Retarded and distinct progress of lens opacification in congenic hereditary cataract mice, Balb/c-nct/nct.

@article{Matsuzawa1988RetardedAD,
  title={Retarded and distinct progress of lens opacification in congenic hereditary cataract mice, Balb/c-nct/nct.},
  author={Akio Matsuzawa and Etsuko Wada},
  journal={Experimental eye research},
  year={1988},
  volume={47 5},
  pages={705-11}
}
The Nakano cataract gene, nct, was introduced into Balb/c mice by repeated backcrosses to elucidate the possible effects of background genes on its expression. The resulting congenic Balb/c-nct/nct mice were characterized by retarded and sporadic cataract formation with a tendency of further retardation in males and by the different disease process of cataract as compared with Nakano mice. The age of 50% cataract incidence was 60 days in females and 90 days in males compared with 22 days in… CONTINUE READING