Retardation by aminoguanidine of development of albuminuria, mesangial expansion, and tissue fluorescence in streptozocin-induced diabetic rat.

@article{SoulisLiparota1991RetardationBA,
  title={Retardation by aminoguanidine of development of albuminuria, mesangial expansion, and tissue fluorescence in streptozocin-induced diabetic rat.},
  author={T. Soulis-Liparota and Marie A. Cooper and Dimitrios Papazoglou and Blaise Clarke and George Jerums},
  journal={Diabetes},
  year={1991},
  volume={40 10},
  pages={1328-34}
}
This study evaluated the relationship between the development of fluorescence related to advanced glycosylation end products (AGEs) in the kidney and experimental diabetic nephropathy over a 32-wk period. Control, untreated diabetic, and aminoguanidine-treated diabetic rats were followed for 32 wk with eight weekly measurements of urinary albumin excretion. After 32 wk, collagen-related fluorescence in aorta and kidney (whole kidney, isolated glomeruli, and renal tubules) and glomerular… CONTINUE READING
141 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 141 extracted citations

Similar Papers

Loading similar papers…