Retaliation against tumor cells showing aberrant HLA expression using lymphokine activated killer-derived T cells.

@article{Falk2002RetaliationAT,
  title={Retaliation against tumor cells showing aberrant HLA expression using lymphokine activated killer-derived T cells.},
  author={Christine S. Falk and Elfriede Noessner and Elisabeth H. Weiss and Dolores J. Schendel},
  journal={Cancer research},
  year={2002},
  volume={62 2},
  pages={480-7}
}
Lymphokine activated killer (LAK) cells represent mixtures of natural killer (NK) and non-MHC-restricted CTLs that have the capacity to lyse a variety of tumor cells and MHC class I-negative target cells. Although it is clear that NK cells are negatively regulated by interactions with MHC class Ia or class Ib molecules, the regulation of LAK-derived T cells has not been clarified to date. In the studies presented here, we demonstrate that IFN-gamma treatment of tumor cells can induce their… CONTINUE READING
12 Citations
60 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 60 references

Cellular and molecular analyses of 486 HLA CLASS I MOLECULES INHIBIT LAK-T CELL ACTIVITY on July 22, 2017

  • D. J. Schendel, R. Oberneder, +6 authors E. Nossner
  • J. Mol. Med.,
  • 2002
1 Excerpt

Modulation of CD3 large granular lymphocyte functions by agonist and antagonists of protein kinase C: effects on NK 485 HLA CLASS I MOLECULES INHIBIT LAK-T CELL ACTIVITY on July 22, 2017

  • J. R. Ortaldo, H. A. Young, L. Varesio
  • J. Immunol.,
  • 2002

The Natural Killer Cell, pp. 1–248

  • C. E. Lewis, J.O.D. McGee
  • 2001
3 Excerpts

Similar Papers

Loading similar papers…