Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.

@article{Bishayee2010ResveratrolSO,
  title={Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.},
  author={Anupam Bishayee and Kendra F. Barnes and Deepak Bhatia and Altaf S. Darvesh and Richard T. Carroll},
  journal={Cancer prevention research},
  year={2010},
  volume={3 6},
  pages={753-63}
}
Hepatocellular carcinoma (HCC), one of the most frequent and deadliest cancers, has been increasing considerably in the United States. In the absence of a proven effective therapy for HCC, novel chemopreventive strategies are urgently needed to lower the current morbidity and mortality of HCC. Recently, we have reported that resveratrol, a compound present in grapes and red wine, significantly prevents diethylnitrosamine (DENA)-induced liver tumorigenesis in rats, although the mechanism of… CONTINUE READING
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