Resveratrol prevents oxidative stress and inhibition of Na(+)K(+)-ATPase activity induced by transient global cerebral ischemia in rats.

@article{Simo2011ResveratrolPO,
  title={Resveratrol prevents oxidative stress and inhibition of Na(+)K(+)-ATPase activity induced by transient global cerebral ischemia in rats.},
  author={Fabr{\'i}cio Sim{\~a}o and Aline Matt{\'e} and Cristiane Matt{\'e} and Fl{\'a}via Mahatma Schneider Soares and Angela T. S. Wyse and Carlos Alexandre Netto and Christianne Gazzana Salbego},
  journal={The Journal of nutritional biochemistry},
  year={2011},
  volume={22 10},
  pages={921-8}
}
Increased oxidative stress and energy metabolism deficit have been regarded as an important underlying cause for neuronal damage induced by cerebral ischemia/reperfusion (I/R) injury. In this study, we investigated the oxidative mechanisms underlying the neuroprotective effects of resveratrol, a potent polyphenol antioxidant found in grapes, on structural and biochemical abnormalities in rats subjected to global cerebral ischemia. Experimental model of transient global cerebral ischemia was… CONTINUE READING
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