Resveratrol inhibits renal interstitial fibrosis in diabetic nephropathy by regulating AMPK/NOX4/ROS pathway

@article{He2016ResveratrolIR,
  title={Resveratrol inhibits renal interstitial fibrosis in diabetic nephropathy by regulating AMPK/NOX4/ROS pathway},
  author={Ting He and Jiachuan Xiong and Ling Nie and Yanlin Yu and Xu Guan and Xinli Xu and Tangli Xiao and Ke Yang and Liang Liu and Daohai Zhang and Yunjian Huang and Jingbo Zhang and Junping Wang and Kumar Sharma and Jinghong Zhao},
  journal={Journal of Molecular Medicine},
  year={2016},
  volume={94},
  pages={1359-1371}
}
Renal interstitial fibrosis is a major pathologic feature of diabetic nephropathy, while the pathogenesis and therapeutic interventions of diabetic renal interstitial fibrosis are not well established. In this study, we first demonstrated that high glucose could induce renal fibroblast (NRK-49F) cell proliferation and activation to myofibroblasts… CONTINUE READING