Resveratrol inhibits migration and Rac1 activation in EGF- but not PDGF-activated vascular smooth muscle cells

Abstract

SCOPE Migration of vascular smooth muscle cells (VSMC) reflects one of the initial steps in atherosclerosis. Resveratrol (RV) is suggested to mediate putative vasoprotective properties of red wine leading to the hypothesis that RV interferes with growth factor-induced migration of VSMC. METHODS AND RESULTS We show here that RV (50 μM) strongly reduces… (More)
DOI: 10.1002/mnfr.201100309

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