Resveratrol inhibits interleukin-6 production in cortical mixed glial cells under hypoxia/hypoglycemia followed by reoxygenation

@article{Wang2001ResveratrolII,
  title={Resveratrol inhibits interleukin-6 production in cortical mixed glial cells under hypoxia/hypoglycemia followed by reoxygenation},
  author={M. J. Wang and H. M. Huang and Shih-an J Hsieh and K-C G Jeng and Jung-hua Steven Kuo},
  journal={Journal of Neuroimmunology},
  year={2001},
  volume={112},
  pages={28-34}
}
Reactive oxygen intermediates (ROIs) are important mediators of a variety of pathological processes, including inflammation and ischemia/reperfusion injury. Cytokines and chemokines are detected at mRNA level in human and animal ischemic brains. This suggests that hypoxia/reoxygenation may induce cytokine production through generation of ROIs. In this study, we investigated the cytokine induction and inhibition by antioxidants in rat cortical mixed glial cells exposed to in vitro ischemia-like… CONTINUE READING

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