Resveratrol inhibits Staphylococcus aureus-induced TLR2/MyD88/NF-κB-dependent VCAM-1 expression in human lung epithelial cells.

@article{Lee2014ResveratrolIS,
  title={Resveratrol inhibits Staphylococcus aureus-induced TLR2/MyD88/NF-$\kappa$B-dependent VCAM-1 expression in human lung epithelial cells.},
  author={I-Ta Lee and Chih-Chung Lin and Chih-Kai Hsu and M. Wu and R. Cho and Chuen-Mao Yang},
  journal={Clinical science},
  year={2014},
  volume={127 6},
  pages={
          375-90
        }
}
Staphylococcus aureus is the most commonly found Gram-positive bacterium in patients admitted to intensive-care units, causing septicaemia or pneumonia. S. aureus is considered to play an important role in the induction of cell adhesion molecules. Resveratrol, a compound found in the skins of red fruits, may inhibit the inflammatory signalling pathways involved in lung diseases. In the present paper, we have shown that resveratrol reduced S. aureus-mediated VCAM-1 (vascular cell adhesion… Expand
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