Resveratrol attenuates ovariectomy-induced hypertension and bone loss in stroke-prone spontaneously hypertensive rats.

@article{Mizutani2000ResveratrolAO,
  title={Resveratrol attenuates ovariectomy-induced hypertension and bone loss in stroke-prone spontaneously hypertensive rats.},
  author={Ken-Ichi Mizutani and Katsumi Ikeda and Yasuaki Kawai and Yukio Yamori},
  journal={Journal of nutritional science and vitaminology},
  year={2000},
  volume={46 2},
  pages={78-83}
}
We examined the effect of resveratrol (3,4',5-trihydroxy stilbene), a phenolic compound found in the skins of most grapes, on blood pressure and bone loss in ovariectomized (OVX), stroke-prone spontaneously hypertensive rats (SHRSP). Nineteen-week-old female SHRSP were divided into a sham-ovariectomized (sham) group fed a control diet and two OVX groups fed either a control diet (OVX-Cont) or a diet supplemented with resveratrol (5 mg/kg per d; OVX-Resv). Ovariectomy induced significant… CONTINUE READING
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