Resveratrol and quercetin, two natural polyphenols, reduce apoptotic neuronal cell death induced by neuroinflammation.

@article{Bureau2008ResveratrolAQ,
  title={Resveratrol and quercetin, two natural polyphenols, reduce apoptotic neuronal cell death induced by neuroinflammation.},
  author={Genevi{\'e}ve Bureau and Fanny Longpr{\'e} and M-G Martinoli},
  journal={Journal of neuroscience research},
  year={2008},
  volume={86 2},
  pages={
          403-10
        }
}
Parkinson's disease (PD) is a movement disorder characterized by a progressive loss of nigrostriatal dopaminergic neurons. Microglia activation and neuroinflammation have been associated with the pathogenesis of PD. Indeed, cytokines have been proposed as candidates that mediate the apoptotic cell death of dopaminergic neurons seen in PD. In this study, we investigated the effect of two natural polyphenols, resveratrol and quercetin, on neuroinflammation. For glial cells, we observed that… CONTINUE READING
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