Resveratrol and Alzheimer’s Disease: Mechanistic Insights

@article{Ahmed2016ResveratrolAA,
  title={Resveratrol and Alzheimer’s Disease: Mechanistic Insights},
  author={Touqeer Ahmed and Sehrish Javed and Sana Javed and Ameema Tariq and Dunja {\vS}amec and Silvia Tejada and Seyed Fazel Nabavi and Nady Braidy and Seyed Mohammad Nabavi},
  journal={Molecular Neurobiology},
  year={2016},
  volume={54},
  pages={2622-2635}
}
Alzheimer’s disease (AD) is the leading cause of dementia in the elderly and is characterized by progressive cognitive and memory deficits. The pathological hallmarks of AD include extracellular senile plaques and intracellular neurofibrillary tangles. Although several mechanisms have been used to explain the underlying pathogenesis of AD, current treatment regimens remain inadequate. The neuroprotective effects of the polyphenolic stilbene resveratrol (3,5,4′-trihydroxy-trans-stilbene) have… Expand
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