Resveratrol ameliorates cardiac oxidative stress in diabetes through deacetylation of NFkB-p65 and histone 3.

@article{Bagul2015ResveratrolAC,
  title={Resveratrol ameliorates cardiac oxidative stress in diabetes through deacetylation of NFkB-p65 and histone 3.},
  author={Pankaj K. Bagul and Nancy Deepthi and Razia Sultana and Sanjay Kumar Banerjee},
  journal={The Journal of nutritional biochemistry},
  year={2015},
  volume={26 11},
  pages={1298-307}
}
Resveratrol, a phytoalexin, has recently gained attention for protective effects against metabolic and cardiac diseases. The beneficial effects of resveratrol have been linked to sirtuin-1 (SIRT-1) activation. However, little is known about the effect of resveratrol in cardiac complications associated with diabetes. Here, we have demonstrated that resveratrol ameliorates cardiac hypertrophy, electrocardiographic abnormalities and oxidative stress in the fructose-fed diabetic rat heart… CONTINUE READING

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