Resveratrol acts as a natural profungicide and induces self-intoxication by a specific laccase.

@article{Schouten2002ResveratrolAA,
  title={Resveratrol acts as a natural profungicide and induces self-intoxication by a specific laccase.},
  author={Alexander Schouten and Lia Wagemakers and Francesca L. Stefanato and Rachel Maria van der Kaaij and Jan A L van Kan},
  journal={Molecular microbiology},
  year={2002},
  volume={43 4},
  pages={883-94}
}
The grapevine (Vitis) secondary metabolite resveratrol is considered a phytoalexin, which protects the plant from Botrytis cinerea infection. Laccase activity displayed by the fungus is assumed to detoxify resveratrol and to facilitate colonization of grape. We initiated a functional molecular genetic analysis of B. cinerea laccases by characterizing laccase genes and evaluating the phenotype of targeted gene replacement mutants. Two different laccase genes from B. cinerea were characterized… CONTINUE READING

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