Resveratrol, a polyphenolic compound in red wine, protects against oxidized LDL-induced cytotoxicity in endothelial cells.

@article{Ou2006ResveratrolAP,
  title={Resveratrol, a polyphenolic compound in red wine, protects against oxidized LDL-induced cytotoxicity in endothelial cells.},
  author={H S Ou and F S Chou and Huey-Min Sheen and Tsung-Min Lin and Ching-Hwa Yang and Wayne Huey-Herng Sheu},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2006},
  volume={364 1-2},
  pages={196-204}
}
BACKGROUND Resveratrol, a polyphenolic constituent of red wine, has antioxidant effects. However, its protective effects against oxLDL-induced endothelial injury remained unclarified. METHODS Primary human umbilical vein endothelial cell cultures (HUVECs) treated with oxLDL (200 microg/ml) were used to explore the protective effect of resveratrol. Cytotoxicity of oxLDL on HUVECs was studied by measuring lactate dehydrogenase (LDH) release, methylthiazol tetrazolium (MTT) and apoptotic cell… CONTINUE READING
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