Resveratrol, a natural dietary phytoalexin, possesses similar properties to hydroxyurea towards erythroid differentiation.

@article{Rodrigue2001ResveratrolAN,
  title={Resveratrol, a natural dietary phytoalexin, possesses similar properties to hydroxyurea towards erythroid differentiation.},
  author={Christelle M Rodrigue and Nicole Arous and Dora Bachir and Juliette Smith-ravin and P. H. Romeo and Fr{\'e}d{\'e}ric Galact{\'e}ros and M. C. Garel},
  journal={British journal of haematology},
  year={2001},
  volume={113 2},
  pages={500-7}
}
Resveratrol, a natural dietary polyphenol, has been postulated to be implicated in the cardioprotective effect of red wine and the low incidence of breast and prostate cancers among vegetarians and Orientals respectively. This compound inhibits ribonucleotide reductase as does hydroxyurea, the first therapeutic agent used in the treatment of sickle cell disease. Using the human erythroleukaemic K562 cell line as an in vitro model, we show here that 50 micromol/l of resveratrol induced a higher… CONTINUE READING
18 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Similar Papers

Loading similar papers…