Resuscitative effect of a gamma-aminobutyric acid B receptor antagonist on gamma-hydroxybutyric acid mortality in mice.

@article{Carai2005ResuscitativeEO,
  title={Resuscitative effect of a gamma-aminobutyric acid B receptor antagonist on gamma-hydroxybutyric acid mortality in mice.},
  author={Mauro A. M. Carai and Giancarlo Colombo and Gian Luigi Gessa},
  journal={Annals of emergency medicine},
  year={2005},
  volume={45 6},
  pages={
          614-9
        }
}
STUDY OBJECTIVE In the present study, a number of compounds were tested to evaluate their efficacy in exerting a protective effect on gamma-hydroxybutyric acid (GHB)-induced mortality in mice. The drugs investigated were the gamma-aminobutyric acid B (GABA B ) receptor antagonist SCH 50911, the GABA A receptor antagonist bicuculline, the benzodiazepine receptor antagonist flumazenil, the putative GHB receptor antagonist NCS-382, the opioid receptor antagonist naltrexone, and the amino acid and… CONTINUE READING

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