Resuscitation with lactated ringer's does not increase inflammatory response in a Swine model of uncontrolled hemorrhagic shock.

@article{Watters2004ResuscitationWL,
  title={Resuscitation with lactated ringer's does not increase inflammatory response in a Swine model of uncontrolled hemorrhagic shock.},
  author={Jennifer M Watters and Susan I. Brundage and Samuel R Todd and Nathan A Zautke and James A. Stefater and Jason C Lam and Patrick J Muller and Darren Jay Malinoski and Martin Schreiber},
  journal={Shock},
  year={2004},
  volume={22 3},
  pages={283-7}
}
Lactated Ringer's (LR) and normal saline (NS) are widely and interchangeably used for resuscitation of trauma victims. Studies show LR to be superior to NS in the physiologic response to resuscitation. Recent in vitro studies demonstrate equivalent effects of LR and NS on leukocytes. We aimed to determine whether LR resuscitation would produce an equivalent inflammatory response compared with normal saline (NS) resuscitation in a clinically relevant swine model of uncontrolled hemorrhagic shock… CONTINUE READING