Resuscitation with diaspirin crosslinked hemoglobin increases cerebral and renal blood perfusion in hemorrhaged rats.

@article{Kumar1997ResuscitationWD,
  title={Resuscitation with diaspirin crosslinked hemoglobin increases cerebral and renal blood perfusion in hemorrhaged rats.},
  author={Arvind Kumar and A P Sen and Pramod R. Saxena and Anil Gulati},
  journal={Artificial cells, blood substitutes, and immobilization biotechnology},
  year={1997},
  volume={25 1-2},
  pages={85-94}
}
Diaspirin crosslinked hemoglobin (DCLHb Baxter Healthcare Corp., Round Lake, IL, USA), a hemoglobin-based blood substitute has been found to be an effective resuscitative agent following hemorrhage in animals. The present study was undertaken to determine the effect of DCLHb on microvascular perfusion in the brain and kidney following hemorrhage in anaesthetized, male Sprague Dawley rats using laser Doppler flowmetry. Hemorrhage was induced by withdrawal of arterial blood at a rate of 0.5 to 1… CONTINUE READING