Results with a new DTP vaccine in Japan.

  title={Results with a new DTP vaccine in Japan.},
  author={Mikio Kimura and N Hikino},
  journal={Developments in biological standardization},
Adverse reactions to DTP became a social problem in Japan in 1975 which brought a fall of immunization rates and an epidemic of pertussis which had its peak in 1979. Development of a new DTP vaccine with less adverse reactions was urgently needed and an acellular pertussis vaccine was developed which has replaced whole cell pertussis vaccines. More than 15 million doses of the new DTP vaccine has been administered since 1981 in Japan. Immunization acceptance reached 80% in 1982 and the… CONTINUE READING