Results of the First Phase I/II Clinical Vaccination Trial With Direct Injection of mRNA

@article{Weide2008ResultsOT,
  title={Results of the First Phase I/II Clinical Vaccination Trial With Direct Injection of mRNA},
  author={Benjamin Weide and Jean-Philippe Carralot and A. Reese and Birgit Scheel and Thomas Kurt Eigentler and Ingmar Hoerr and Hans-Georg Rammensee and Claus Garbe and Steve Pascolo},
  journal={Journal of Immunotherapy},
  year={2008},
  volume={31},
  pages={180-188}
}
Vaccination against tumor antigens has been shown to be a safe and efficacious prophylactic and therapeutic antitumor treatment in many animal models. Clinical studies in humans indicate that specific immunotherapy can also result in clinical benefits. The active pharmaceutical ingredient in such vaccines can be DNA, RNA, protein, or peptide and can be administered naked, encapsulated, or after delivery in vitro into cells that are then adoptively transferred. One of the easiest, most versatile… 
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