Results of a randomized phase III trial of mirabegron in patients with overactive bladder.

@article{Nitti2013ResultsOA,
  title={Results of a randomized phase III trial of mirabegron in patients with overactive bladder.},
  author={Victor W. Nitti and Stephen M Auerbach and Nancy K. Martin and Alaina Calhoun and Misun Lee and Sender Herschorn},
  journal={The Journal of urology},
  year={2013},
  volume={189 4},
  pages={
          1388-95
        }
}
PURPOSE Many patients with overactive bladder discontinue pharmacotherapy due to suboptimal efficacy or side effects. Mirabegron, a β3-adrenoceptor agonist, may offer an effective and well tolerated alternative treatment for overactive bladder. MATERIALS AND METHODS A randomized, double-blind, placebo controlled trial was conducted in the United States and Canada. After a 2-week placebo run-in period, adults with overactive bladder symptoms for 3 or more months were randomized 1:1:1 to… CONTINUE READING

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