Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States

  title={Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States},
  author={G. Ostapowicz and R. Fontana and Frank Schidt and A. Larson and T. Davern and S. Han and T. Mccashland and A. Shakil and J. E. Hay and L. Hynan and J. Crippin and A. Blei and G. Samuel and J. Reisch and W. Lee},
  journal={Annals of Internal Medicine},
  • G. Ostapowicz, R. Fontana, +12 authors W. Lee
  • Published 2002
  • Medicine
  • Annals of Internal Medicine
  • Context Acute liver failure is a catastrophic condition affecting about 2000 persons in the United States each year. Contribution Among 308 consecutive patients with liver failure admitted to 1 of 17 referral centers between 1998 and 2001, acetaminophen overdose (39%) and idiosyncratic drug reactions (13%) were the most common cause of disease. Sixty-seven percent of patients were still living 3 weeks after presentation (44% without liver transplantation and 23% after transplantation). Survival… CONTINUE READING
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    The purpose of this study is to collect clinical and epidemiological data as well as serum, plasma, urine, tissue and DNA samples on individuals who have acute liver failure and on… Expand
    ConditionsAcute Liver Failure, Acute Liver Injury, Fulminant Hepatic Failure
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