Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States

@article{Ostapowicz2002ResultsOA,
  title={Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States},
  author={George Ostapowicz and Robert John Fontana and Frank Schidt and Anne M. Larson and Timothy J. Davern and Steven‐Huy B. Han and Timothy Mccashland and A. Obaid Shakil and J. Eileen Hay and Linda S. Hynan and Jeffrey S. Crippin and Andres T. Blei and Grace Samuel and Joan S. Reisch and William M. Lee},
  journal={Annals of Internal Medicine},
  year={2002},
  volume={137},
  pages={947-954}
}
Context Acute liver failure is a catastrophic condition affecting about 2000 persons in the United States each year. Contribution Among 308 consecutive patients with liver failure admitted to 1 of 17 referral centers between 1998 and 2001, acetaminophen overdose (39%) and idiosyncratic drug reactions (13%) were the most common cause of disease. Sixty-seven percent of patients were still living 3 weeks after presentation (44% without liver transplantation and 23% after transplantation). Survival… 
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Etiologies and outcomes of acute liver failure in Germany.
  • J. HademF. Tacke A. Canbay
  • Medicine
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
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Acute liver failure.
TLDR
The causes and clinical manifestations of acute liver failure are outlined, current approaches to patient care are discussed, and rates of survival have improved substantially in recent years through advances in critical care management and the use of emergency liver transplantation.
Acute liver failure.
TLDR
The causes and clinical manifestations of acute liver failure are outlined, current approaches to patient care are discussed, and rates of survival have improved substantially in recent years through advances in critical care management and the use of emergency liver transplantation.
Efficacy of liver transplantation for acute hepatic failure: a single-center experience.
Etiologies and Outcomes of Acute Liver Failure in a Spanish Community
Previous retrospective study (1992 to 2000) performed in Spain showed that drug toxicity, viral hepatitis, and indeterminate etiology were the most prevalent causes of acute liver failure (ALF). In
Acute liver failure.
Acute liver failure in Spain: Analysis of 267 cases
  • À. EscorsellA. MasM. L. de la Mata
  • Medicine
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2007
TLDR
Hepatitis B virus is the most common cause of ALF in Spain, although the origin of 30% of cases remains undetermined, and acetaminophen overdose represents a very rare cause.
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