Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States
@article{Ostapowicz2002ResultsOA, title={Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States}, author={George Ostapowicz and Robert John Fontana and Frank Schidt and Anne M. Larson and Timothy J. Davern and Steven‐Huy B. Han and Timothy Mccashland and A. Obaid Shakil and J. Eileen Hay and Linda S. Hynan and Jeffrey S. Crippin and Andres T. Blei and Grace Samuel and Joan S. Reisch and William M. Lee}, journal={Annals of Internal Medicine}, year={2002}, volume={137}, pages={947-954} }
Context Acute liver failure is a catastrophic condition affecting about 2000 persons in the United States each year. Contribution Among 308 consecutive patients with liver failure admitted to 1 of 17 referral centers between 1998 and 2001, acetaminophen overdose (39%) and idiosyncratic drug reactions (13%) were the most common cause of disease. Sixty-seven percent of patients were still living 3 weeks after presentation (44% without liver transplantation and 23% after transplantation). Survival…
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