• DOI:10.7326/0003-4819-137-12-200212170-00007
Corpus ID: 11390513

Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States

@article{Ostapowicz2002ResultsOA,
  title={Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States},
  author={G. Ostapowicz and R. Fontana and Frank Schidt and A. Larson and T. Davern and S. Han and T. Mccashland and A. Shakil and J. E. Hay and L. Hynan and J. Crippin and A. Blei and G. Samuel and J. Reisch and W. Lee},
  journal={Annals of Internal Medicine},
  year={2002},
  volume={137},
  pages={947-954}
}

G. Ostapowicz, R. Fontana, +12 authors W. Lee

Published 2002

Medicine

Annals of Internal Medicine

Context Acute liver failure is a catastrophic condition affecting about 2000 persons in the United States each year. Contribution Among 308 consecutive patients with liver failure admitted to 1 of 17 referral centers between 1998 and 2001, acetaminophen overdose (39%) and idiosyncratic drug reactions (13%) were the most common cause of disease. Sixty-seven percent of patients were still living 3 weeks after presentation (44% without liver transplantation and 23% after transplantation). Survival… CONTINUE READING

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