Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery.

@article{Mazer2017RestrictiveOL,
  title={Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery.},
  author={Cyril David Mazer and Richard Paul Whitlock and Dean Fergusson and Judith Lynne Elliott Hall and Emilie P Belley-C{\^o}t{\'e} and Katherine Ann Connolly and Boris Khanykin and Alexander John Gregory and {\'E}tienne de M{\'e}dicis and Shay McGuinness and Alistair Royse and François Martin Carrier and Paul J Young and Juan Carlos Villar and Hilary P. Grocott and Manfred Daniel Seeberger and Stephen E. Fremes and Francois Lellouche and Summer Syed and Kelly Patrick Anthony Byrne and Sean M Bagshaw and Nian Chih Hwang and Chirag Mukesh Mehta and Thomas W Painter and Colin Forbes Royse and Subodh Verma and Gregory M. T. Hare and Ashley Cohen and Kevin E. Thorpe and Peter J{\"u}ni and Nadine Shehata},
  journal={The New England journal of medicine},
  year={2017},
  volume={377 22},
  pages={
          2133-2144
        }
}
BACKGROUND The effect of a restrictive versus liberal red-cell transfusion strategy on clinical outcomes in patients undergoing cardiac surgery remains unclear. METHODS In this multicenter, open-label, noninferiority trial, we randomly assigned 5243 adults undergoing cardiac surgery who had a European System for Cardiac Operative Risk Evaluation (EuroSCORE) I of 6 or more (on a scale from 0 to 47, with higher scores indicating a higher risk of death after cardiac surgery) to a restrictive red… CONTINUE READING

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