Restrictive diastolic abnormalities identified by Doppler echocardiography in patients with thalassemia major.

@article{Spirito1990RestrictiveDA,
  title={Restrictive diastolic abnormalities identified by Doppler echocardiography in patients with thalassemia major.},
  author={P. Spirito and Gabriele Lupi and Caterina Melevendi and Carlo Vecchio},
  journal={Circulation},
  year={1990},
  volume={82 1},
  pages={88-94}
}
The consequences of transfusional iron overload on left ventricular diastolic filling have never been investigated systematically in patients with thalassemia major. In the present study, the pattern of left ventricular filling was assessed by Doppler echocardiography in 32 patients with thalassemia major (age, 17 +/- 5 years) who had not experienced… CONTINUE READING