Restriction of the Xenopus DEADSouth mRNA to the primordial germ cells is ensured by multiple mechanisms

@article{Yamaguchi2014RestrictionOT,
  title={Restriction of the Xenopus DEADSouth mRNA to the primordial germ cells is ensured by multiple mechanisms},
  author={Takeshi Yamaguchi and Kensuke Kataoka and Kenji Watanabe and Hidefumi Orii},
  journal={Mechanisms of Development},
  year={2014},
  volume={131},
  pages={15-23}
}
DEADSouth mRNA encoding the RNA helicase DDX25 is a component of the germ plasm in Xenopus laevis. We investigated the mechanisms underlying its specific mRNA expression in primordial germ cells (PGCs). Based on our previous findings of several microRNA miR-427 recognition elements (MREs) in the 3' untranslated region of the mRNA, we first examined whether… CONTINUE READING