Restriction endonuclease analysis of Marek's disease virus DNA and homology between strains.

@article{Ross1983RestrictionEA,
  title={Restriction endonuclease analysis of Marek's disease virus DNA and homology between strains.},
  author={L. J. N. Ross and B S Milne and Peter M Biggs},
  journal={The Journal of general virology},
  year={1983},
  volume={64 ( Pt 12)},
  pages={2785-90}
}
The restriction endonuclease patterns of viral DNA obtained from serotypes 1 and 2 strains of Marek's disease virus have been compared and homology between the strains examined by hybridization. The results have shown that HPRS 16 (serotype 1) DNA has a structure similar to its attenuated variant HPRS 16/att except for a few fragments that are present only in the virulent strain. Evidence was obtained which suggested that these restriction fragments contained repeat sequences and that insertion… CONTINUE READING