Restricting the Mobility of GsR: Impact on Receptor and Effector Coupling

Abstract

The R-subunit of the stimulatory G protein, Gs, has been shown to dissociate from the plasma membrane into the cytosol following activation by G protein-coupled receptors (GPCR) in some experimental systems. This dissociation may involve depalmitoylation of an amino-terminal cysteine residue. However, the functional significance of this dissociation is not… (More)

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Cite this paper

@inproceedings{Lee1999RestrictingTM, title={Restricting the Mobility of GsR: Impact on Receptor and Effector Coupling}, author={Tae Weon Lee and Roland Seifert and Xiaoming Guan and Brian K. Kobilka and H Velocity Hughes}, year={1999} }