Restricted transgene expression in the brain with cell-type specific neuronal promoters.

@article{Delzor2012RestrictedTE,
  title={Restricted transgene expression in the brain with cell-type specific neuronal promoters.},
  author={Aur{\'e}lie Delzor and Noelle Dufour and Fanny Petit and Martine Guillermier and Diane Houitte and Gwennaelle Auregan and Emmanuel Brouillet and Philippe Hantraye and Nicole D{\'e}glon},
  journal={Human gene therapy methods},
  year={2012},
  volume={23 4},
  pages={242-54}
}
Tissue-targeted expression is of major interest for studying the contribution of cellular subpopulations to neurodegenerative diseases. However, in vivo methods to investigate this issue are limited. Here, we report an analysis of the cell specificity of expression of fluorescent reporter genes driven by six neuronal promoters, with the ubiquitous phosphoglycerate kinase 1 (PGK) promoter used as a reference. Quantitative analysis of AcGFPnuc expression in the striatum and hippocampus of rodents… CONTINUE READING
8 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…