Restricted or severely hindered diffusion of intramyocellular lipids in human skeletal muscle shown by in vivo proton MR spectroscopy.

@article{Brandejsky2012RestrictedOS,
  title={Restricted or severely hindered diffusion of intramyocellular lipids in human skeletal muscle shown by in vivo proton MR spectroscopy.},
  author={Vaclav Brandejsky and Roland Kreis and Chris Boesch},
  journal={Magnetic resonance in medicine},
  year={2012},
  volume={67 2},
  pages={
          310-6
        }
}
Although magnetic resonance spectroscopy can be used as a unique tool to study molecular diffusion, it is rarely used to measure the diffusion properties of intramyocellular and extramyocellular lipids. Lipids have very low apparent diffusion coefficients (ADCs), which make these measurements difficult and necessitate strong diffusion gradients and long diffusion times. Consequence is that these measurements have inherently low signal-to-noise ratio and are prone to artifacts. The addition of… CONTINUE READING
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