Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues.

  title={Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues.},
  author={Johannes M. Breuss and Nancy A. Gillett and Li Lu and Dean Sheppard and Robert Pytela},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  volume={41 10},
Integrins are cell adhesion receptors that mediate cell-extracellular matrix and cell-cell interactions. Each integrin consists of two glycoprotein subunits (alpha and beta). We have previously described a novel integrin beta-subunit, beta 6, which is expressed in cultured epithelial cells. beta 6 can associate with alpha v to form the fibronectin-binding heterodimer alpha v beta 6. Here we report the tissue distribution of beta 6 integrin mRNA determined by in situ hybridization of a beta 6… CONTINUE READING


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