Restricted SIV replication in rhesus macaque lung tissues during the acute phase of infection.

@article{Fuller2002RestrictedSR,
  title={Restricted SIV replication in rhesus macaque lung tissues during the acute phase of infection.},
  author={Craig L. Fuller and Yang Kyu Choi and Beth A. Fallert and Saverio Capuano and Premeela Rajakumar and Michael A. Murphey-Corb and Todd A. Reinhart},
  journal={The American journal of pathology},
  year={2002},
  volume={161 3},
  pages={969-78}
}
The extent to which simian immunodeficiency virus (SIV) replication in lung tissues contributes to the pool of viruses replicating during acute infection is incompletely understood. To address this issue, in situ hybridization was used to examine SIV replication in multiple lobes of lung from rhesus macaques infected with pathogenic SIV. Despite widespread viral replication in lymphoid and intestinal tissues, the lungs during acute infection harbored rare productively infected cells… CONTINUE READING

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