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# Restricted Likelihood Ratio Tests in Nonparametric Longitudinal Models

@inproceedings{Crainiceanu2004RestrictedLR, title={Restricted Likelihood Ratio Tests in Nonparametric Longitudinal Models}, author={Ciprian M. Crainiceanu and David Ruppert}, year={2004} }

- Published 2004

We assume that repeated measurements are taken on each of several subjects that are randomly sampled from some population. The observations on a particular subject are expressed as the sum of an average curve for the population and a deviation of the subject’s curve from the average plus independent errors. Both curves are modeled nonparametrically as splines. We use roughness penalties on the splines, which is equivalent to assuming a linear mixed model. Within this linear mixed model, we… CONTINUE READING

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