Restraint stress induced gut dysmotility is diminished by a milk oligosaccharide (2′-fucosyllactose) in vitro

@inproceedings{Farhin2019RestraintSI,
  title={Restraint stress induced gut dysmotility is diminished by a milk oligosaccharide (2′-fucosyllactose) in vitro},
  author={Sohana Farhin and Annette Kuuipolani Wong and Thilini Delungahawatta and Jessica Y. Amin and John Bienenstock and Rachael H. Buck and Wolfgang A Kunze},
  booktitle={PloS one},
  year={2019}
}
BACKGROUND Stress causes severe dysmotility in the mammalian gut. Almost all research done to date has concentrated on prevention of stress-induced altered gut motility but not on treatment. We had previously shown that intraluminal 2'FL could acutely moderate propulsive motility in isolated mouse colonic segments. Because 2'FL appeared to modulate enteric nervous system dependent motility, we wondered if the oligosaccharide could reverse the effects of prior restraint stress, ex vivo. We… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 36 REFERENCES

Lactobacillus rhamnosus strain JB-1 reverses restraint stress-induced gut dysmotility.

  • Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • 2017

Endogenous CRF in rat large intestine mediates motor and secretory responses to stress.

  • Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • 2016

Probiotic Lactobacillus casei strain Shirota relieves stress-associated symptoms by modulating the gut-brain interaction in human and animal models.

  • Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • 2016