Restoration of visual cortical plasticity by local microperfusion of norepinephrine.

@article{Kasamatsu1979RestorationOV,
  title={Restoration of visual cortical plasticity by local microperfusion of norepinephrine.},
  author={Takuji Kasamatsu and John D. Pettigrew and M B Ary},
  journal={The Journal of comparative neurology},
  year={1979},
  volume={185 1},
  pages={163-81}
}
Using a newly developed technique of continuous microperfusion, we obtained further evidence in support of our hypothesis that the neocortical catecholamines (CAs), particularly norepinephrine (NE), are responsible for a high level of cortical plasticity. We used the visual cortical changes in ocular dominance which follow a brief monocular deprivation as a simple and reliable index of cortical plasticity. Local perfusion of kitten visual cortex with 1 mg/ml (4.0 mM) 6-hydroxydopamine (6-OHDA… CONTINUE READING