Restoration of spinal bone in osteoporotic men by treatment with human parathyroid hormone (1-34) and 1,25-dihydroxyvitamin D.

@article{Slovik1986RestorationOS,
  title={Restoration of spinal bone in osteoporotic men by treatment with human parathyroid hormone (1-34) and 1,25-dihydroxyvitamin D.},
  author={David M Slovik and Daniel I. Rosenthal and Samuel H. Doppelt and John T. Potts and Margaret A Daly and James A. Campbell and Robert M. Neer},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1986},
  volume={1 4},
  pages={377-81}
}
Daily subcutaneous injection of a synthetic human parathyroid hormone fragment, combined with daily ingestion of 1,25(OH)2 vitamin D, significantly increased trabecular bone density in the spine (p less than .01), and improved intestinal calcium and phosphorus absorption and total body retention of dietary calcium and phosphorus in middle-aged men with idiopathic osteoporosis. The increases in spinal bone mineral were marked and progressive during a year of treatment. These results indicate… CONTINUE READING