Restoration of normal sperm characteristics in hypoprolactinemic infertile men treated with metoclopramide and exogenous human prolactin

@article{Ufearo1995RestorationON,
  title={Restoration of normal sperm characteristics in hypoprolactinemic infertile men treated with metoclopramide and exogenous human prolactin},
  author={C. S. Ufearo and Orish Ebere Orisakwe},
  journal={Clinical Pharmacology \& Therapeutics},
  year={1995},
  volume={58}
}

Semen quality in patients with pituitary disease and adult-onset hypogonadotropic hypogonadism

The majority presented with normal semen quality based on the determination of the number of progressively motile spermatozoa and the data suggest reduced LH bioactivity in patients with pituitary insufficiency.

Therapeutic effects of Schisandra chinensis on the hyperprolactinemia in rat.

Results show that S. chinensis and its single compound, gomisin N, are regulators of PRL production and may be candidates for treatment of hyperprolactinemia and prolactinoma.

An investigation of the effectiveness of testosterone implants in combination with the prolactin inhibitor quinagolide in the suppression of spermatogenesis in men.

Results show that inhibition of PRL does not to confer additional efficacy in spermatogenic suppression in men, and Q did not totally block PRL secretion in the subjects, possibly because testosterone replacement itself stimulated PRL by a direct action on the lactotroph, thus the effectiveness of dual inhibition of gonadotrophin and PRL could be fully investigated.

The role of prolactin in andrology: what is new?

There is significant evidence supporting the hypothesis that PRL could be a mirror of serotonin in the brain, and an association with anxiety or depressive symptoms has been found in men with sexual dysfunction and from the general European population.

Prolactin serum concentrations during aripiprazole treatment in youth.

With the increasing use of aripiprazole in the United States population, it is important that future research be conducted to explore the potential sequelae of subnormal PRL serum levels in children and adolescents.

Effect of diclofenac on semen quality: A review

Diclofenac appears to induce negative effects on both qualitative and quantitative measures of sperm; however, this conclusion requires confirmation by human studies.

A case of risperidone-induced priapism in a patient with glucose-6-phosphate dehydrogenase deficiency

A case of risperidone-induced priapism in a man with glucose-6-phosphate dehydrogenase (G6PD) deficiency is presented.

Plasma Concentration of Prolactin, Testosterone Might Be Associated with Brain Response to Visual Erotic Stimuli in Healthy Heterosexual Males

The results suggested sexual hormones in basal state may have their specific target regions or network associated with sexual response, and positively associated with brain activity of the bilateral supplementary motor area which related with motivational component of sexual behavior.

Aripiprazole-Induced Hypoprolactinemia in an Adult Male with First-Episode Psychosis.

A case of aripiprazole-induced hypoprolactinemia in an adult male with first-episode psychosis is reported, and the possible effects of abnormally low prolactin are discussed.

Preclinical risk assessment of drug‐induced hypo‐ and hyperprolactinemia

It is shown that classic hallmarks of hypo‐/hyperprolactinemia can be recognized in short‐ and long‐term rodent bioassays and taken together with human epidemiological evidence pertaining to the consequences of drug‐induced hypo-/hyper Prolactin signaling permit both an analysis of human relevance and an assessment of human risk.

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