Restoration of normal sperm characteristics in hypoprolactinemic infertile men treated with metoclopramide and exogenous human prolactin

@article{Ufearo1995RestorationON,
  title={Restoration of normal sperm characteristics in hypoprolactinemic infertile men treated with metoclopramide and exogenous human prolactin},
  author={C. S. Ufearo and Orish Ebere Orisakwe},
  journal={Clinical Pharmacology \& Therapeutics},
  year={1995},
  volume={58}
}
We investigated the effects of induced increase in prolactin levels on spermatogenesis in 20 infertile men with hypoprolactinemia using exogenous human prolactin (hPRL) and metoclopramide. The subjects were selected from a population of 175 infertile men in whom the prevalence of hypoprolactinemia was 33.14%. Mean basal plasma prolactin was 2.79 ± 0.62 ng · ml−1 in the infertile men and 9.57 ± 2.14 ng · ml−1 in the normal control subjects. At the sixteenth week, mean plasma prolactin was 9.41… Expand
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