Restoration of disturbed intracortical motor inhibition and facilitation in attention deficit hyperactivity disorder children by methylphenidate.

@article{Buchmann2007RestorationOD,
  title={Restoration of disturbed intracortical motor inhibition and facilitation in attention deficit hyperactivity disorder children by methylphenidate.},
  author={Johannes Buchmann and Wolfgang Gierow and Simone N. Weber and Jacqueline Hoeppner and Thomas Klauer and Reiner Benecke and Frank Walter H{\"a}\ssler and Alexander Wolters},
  journal={Biological psychiatry},
  year={2007},
  volume={62 9},
  pages={963-9}
}
BACKGROUND Previous investigations using transcranial magnetic stimulation (TMS) have shown that neural inhibitory motor circuits are disturbed in ADHD children. We sought to investigate the influence of methylphenidate (MPH) on inhibitory and facilitatory motor circuits of ADHD children with TMS paired pulse protocols using surplus long interval inter-stimulus intervals (ISI) not investigated so far. METHODS Motorcortical modulation was tested with TMS paired pulse protocols employing ISI of… CONTINUE READING