Restoration of coronary endothelial function in obese Zucker rats by a low-carbohydrate diet.

@article{Focardi2007RestorationOC,
  title={Restoration of coronary endothelial function in obese Zucker rats by a low-carbohydrate diet.},
  author={Marta Focardi and Gregory M. Dick and Andrea Picchi and Cuihua Zhang and William M. Chilian},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2007},
  volume={292 5},
  pages={
          H2093-9
        }
}
A popular diet used for weight reduction is the low-carbohydrate diet, which has most calories derived from fat and protein, but effects of this dietary regimen on coronary vascular function have not been identified. We tested the hypothesis that obesity-induced impairment in coronary endothelial function is reversed by a low-carbohydrate diet. We used four groups of male Zucker rats: lean and obese on normal and low-carbohydrate diets. Rats were fed ad libitum for 3 wk; total caloric intake… Expand
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