Restoration of circadian behavioural rhythms by gene transfer in Drosophila

@article{Bargiello1984RestorationOC,
  title={Restoration of circadian behavioural rhythms by gene transfer in Drosophila},
  author={T. Bargiello and F. Jackson and M. Young},
  journal={Nature},
  year={1984},
  volume={312},
  pages={752-754}
}
The per locus of Drosophila melanogaster has a fundamental role in the construction or maintenance of a biological clock. Three classes of per mutations have been identified: perl mutants have circadian behavioural rhythms with a 29-h rather than a 24-h period, pers mutants have short-period rhythms of 19 h, and per0 mutants have no detectable circadian rhythms1–4. Each of these mutations has a corresponding influence on the 55-s periodicity of male courtship song5. Long-and short-period… Expand
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