Restoration of Self-awareness of Hypoglycemia in AdultsWith Long-standing Type 1 Diabetes Hyperinsulinemic-hypoglycemic clamp substudy results from the HypoCOMPaSS trial

@inproceedings{Leelarathna2013RestorationOS,
  title={Restoration of Self-awareness of Hypoglycemia in AdultsWith Long-standing Type 1 Diabetes Hyperinsulinemic-hypoglycemic clamp substudy results from the HypoCOMPaSS trial},
  author={L Leelarathna and Stuart and A.. and Little and Emma Walkinshaw and Horng Kai Tan and Alexandra Lubina and Solomon and Kavita Kumareswaran and ANNETTE and P................... and Lane and Thomas B. Chadwick and Sally and M.. and Marshall and Jane Speight and Daniel P Flanagan and Simon and R. and Heller and James and A. Mirzaei and Shaw and N C Mark and L.. and Evans},
  year={2013}
}
OBJECTIVEdImpaired awareness of hypoglycemia (IAH) and defective counterregulation significantly increase severe hypoglycemia risk in type 1 diabetes (T1D). We evaluated restoration of IAH/defective counterregulation by a treatment strategy targeted at hypoglycemia avoidance in adults with T1D with IAH (Gold score $4) participating in the U.K.-based multicenter HypoCOMPaSS randomized controlled trial. 

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