Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health.

  title={Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health.},
  author={Richard P. Allen and Daniel L. Picchietti and W. Hening and Claudia Trenkwalder and Arthur S. Walters and Jacques Montplaisi},
  journal={Sleep medicine},
  volume={4 2},

Restless legs syndrome / Willis – Ekbom disease diagnostic criteria : updated International Restless Legs

The IRLSSG consensus criteria for RLS/WED represent an international, interdisciplinary, and collaborative effort intended to improve clinical practice and promote further research.

Risk Factors and Treatment of Restless Legs Syndrome in Adults

This syndrome has been sub optimally diagnosed in the past and remains overall misunderstood and under-recognized by many primary health care providers, however, RLS is increasingly recognized to cause significant disease burden and decreased quality of life.

Restless Legs Syndrome: Prevalence and Impact in Children and Adolescents—The Peds REST Study

These population-based data suggest that restless legs syndrome is prevalent and troublesome in children and adolescents, occurring more commonly than epilepsy or diabetes.

Algorithms for the diagnosis and treatment of restless legs syndrome in primary care

BackgroundRestless legs syndrome (RLS) is a neurological disorder with a lifetime prevalence of 3-10%. in European studies. However, the diagnosis of RLS in primary care remains low and mistreatment

Restless Legs Syndrome, the Pitfall: Hardly Diagnosed and Rarely Treated Neurological Disease

The exact pathophysiology of the RLS is still not clear, but some superficial assumptions regarding the progressions of disease and root of disease through the gene molecular concepts are made, although genetic biomarkers have been developed for the diagnosis of the disease.

Restless legs syndrome: diagnosis, epidemiology, classification and consequences

Higher awareness of RLS among physicians is required; it remains an underdiagnosed clinical condition.



Restless legs syndrome in childhood: A consensus proposal for diagnostic criteria

SummaryNo previous studies have explicitly addressed the issue of diagnostic criteria for restless legs syndrome (RLS) in children. Diagnosis of RLS in adults is primarily based on the patient's

Toward a better definition of the restless legs syndrome

Features commonly seen in RLS include sleep disturbance, periodic limb movements in sleep and similar involuntary movements while awake, a normal neurological examination in the idiopathic from, a tendency for the symptoms to be worse in middle to older age, and, in some cases, a family history suggestive of an autosomal dominant mode of inheritance.

Restless legs syndrome: a review for the renal care professionals.

  • T. Wetter
  • Medicine, Psychology
    EDTNA/ERCA journal
  • 2001
In secondary restless legs syndrome the underlying illness should be treated first, but dopaminergic drugs may also be helpful; however, the development of augmentation of symptoms especially under levodopa therapy may be a major problem.

A questionnaire study of 138 patients with restless legs syndrome

A telephone survey of their symptomatology found that more than a third of the patients in each group experienced their first symptoms before the age of 20 and in the older age-onset patients, misdiagnoses also included skin irritation, arthritis, and malingering.

Clinical characteristics and frequency of the hereditary restless legs syndrome in a population of 300 patients.

It is shown that patients with hereditary RLS may experience an earlier onset of the disease, compared to those of non-hereditary RLS, which was similar in both groups.

Restless Legs Syndrome: A Clinical Study of 55 Patients

RLS is a clinically pleomorphic syndrome, reflecting the contribution of multiple genetic and acquired factors in the pathogenesis of RLS.

Restless Legs Syndrome: A Review of Clinical and Pathophysiologic Features

  • R. AllenC. Earley
  • Medicine, Biology
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
  • 2001
This review of RLS covers history, diagnosis, morbidity of sleep disturbance, relation to periodic limb movements in both sleep and waking, secondary causes, severity assessment methods, phenotypes for possible genetic patterns, epidemiology, pathophysiology, and medical treatmentconsiderations.

Epidemiology of restless legs symptoms in adults.

The prevalence of restless legs in the general adult population is high and may be associated with decreased well-being, emphasizing the need for further research and greater medical recognition of this condition.

Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: A study of 133 patients diagnosed with new standard criteria

A strong relationship was found between these complaints and polysomnographic findings; increasing sleep latency and number of awakenings and decreasing sleep efficiency were associated with worsening symptoms.