Resting state sensorimotor functional connectivity in multiple sclerosis inversely correlates with transcallosal motor pathway transverse diffusivity.

@article{Lowe2008RestingSS,
  title={Resting state sensorimotor functional connectivity in multiple sclerosis inversely correlates with transcallosal motor pathway transverse diffusivity.},
  author={Mark J. Lowe and Erik B. Beall and Ken E. Sakaie and Katherine Koenig and Lael Stone and Ruth Ann Marrie and Michael D. Phillips},
  journal={Human brain mapping},
  year={2008},
  volume={29 7},
  pages={818-27}
}
Recent studies indicate that functional connectivity using low-frequency BOLD fluctuations (LFBFs) is reduced between the bilateral primary sensorimotor regions in multiple sclerosis. In addition, it has been shown that pathway-dependent measures of the transverse diffusivity of water in white matter correlate with related clinical measures of functional deficit in multiple sclerosis. Taken together, these methods suggest that MRI methods can be used to probe both functional connectivity and… CONTINUE READING